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MET Amplification

Poor Prognosis
1.50% Prevalence Level 3 Rare Fusions
Genes Involved
MET
Treatment Implications

Associated with poor prognosis and anti-EGFR resistance.

Recommended Treatments
Treatments to Avoid
Anti-EGFR if amplified
Study References

Resistance studies

Key Statistics
1.50%
Prevalence in CRC
No
Targetable
Clinical Notes
May emerge on anti-EGFR treatment.
Information

Category: Rare Fusions

Evidence Level: Level 3

Last Updated: Dec 7, 2025

Medical Disclaimer: This information is for educational purposes only and should not replace professional medical advice. Always consult with your oncologist for personalized treatment decisions based on your specific situation.