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MET Amplification + RAS WT
Intermediate PrognosisGenes Involved
MET Amplification
RAS Wild-type
Recommended Treatments
MET inhibitors (clinical trials)
Capmatinib
Tepotinib
Treatments to Avoid
No specific contraindications noted
Key Statistics
2.00%
Prevalence in CRC
Yes
Targetable
Clinical Notes
May emerge as resistance mechanism to anti-EGFR therapy. MET inhibitors in development.
Information
Category: General
Evidence Level: C
Medical Disclaimer: This information is for educational purposes only and should not replace professional medical advice. Always consult with your oncologist for personalized treatment decisions based on your specific situation.